Ovulation Induction (“OI”)

On this page:

  1. What Is Ovulation Induction (OI)?
  2. How Does OI Work?
  3. Possible Risks.
  4. When Is OI Used?
  5. Find Out More.

What is Ovulation Induction (“OI”)

Ovulation Induction (“OI”) is a fertility treatment where medication is used to stimulate the ovaries with the intention of producing and ovulating a single egg. This is typically done using one of two drugs, Clomiphene Citrate ( Clomid® ) also known as Serophene®, or Follicle Stimulating Hormone (“FSH”). Ovulation then occurs or is induced and conception is achieved through intercourse.

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How Does OI Work?

  1. Step 1 – Stimulation (using Clomid or FSH) -  Clomid OI - Clomid (an oral medication) is taken for 5 days at the beginning of the menstrual cycle. The cycle is then monitored with blood tests and scan(s) to determine response to the Clomid and ovulation.  FSH is given in the form of daily injections.  A low dose of FSH is administered daily from day 5 (approximately) of the menstrual cycle.  The cycle is then monitored with blood tests and scans to determine response to the injections and ovulation.
  2. Step 2 – Ovulation – Intercourse is advised around the time of ovulation. Sometimes a trigger injection is required to induce ovulation.
  3. Step 3 – Luteal Phase – luteal blood tests are  taken approximately 4 and 7 days after ovulation and a blood test for pregnancy approximately 18 days after ovulation. Luteal support (usually in the form of progesterone pessaries) is sometimes given following ovulation to ensure adequate progesterone levels and maintain the uterine lining.

For further information on the process of OI at Flinders Fertility please open or download our "OI Brochure" (pdf 0.97MB).

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Possible Risks

Possible risks include:

  1. Multiple pregnancies if 2 or more follicles develop and ovulate.
  2. Ovarian Hyperstimulation Syndrome (“OHSS”) may occur when the ovaries are over stimulated by fertility medication.  This condition is rare and symptoms include bloated and sore abdomen, nausea and vomiting, shortness of breath and reduced urine output. 
  3. Common side effects of medication can include - Mood swings, tender breasts, abdominal discomfort & bloating.

For more information, please open or download our "OI Risks" Information Statement. 

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When Is OI Used?

OI is used when women are experiencing ovulation problems. A common symptom of ovulation problems is absence of menstruation or irregular menstrual cycles.

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Find Out More

At Flinders Fertility we recognise that a website may not cover all your information requirements.  That's why we offer a number of information options. So, if you want to find out more about OI, either:

  1. Call on 131 IVF (131 483) to talk to one of our Fertility Specialists.
  2. Email us at enquire@flindersfertility.com.au.
  3. Seek a referral to Flinders Fertility from your Doctor.

If you require the aid of an interpreter please let us know, as well as any specific regional dialect that you may require.


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